From my part-time job. I've been working 2 days a week (nominally) for another science business doing R&D for their customers. Back in the summer I realised that I was bringing far too much of the writing up and analysis work back, and it was compromising both their work and mine. Combined with the fact that we finished last year with (a little) more money in the bank than we started plus quite a bit of prayer it seemed right that I should resign.
So it should have all finished in December, but with my cold etc I just couldn't make it in for that last week's work and hand-over of all lab books etc. That finally happened today, and although there are bound to be questions etc about things that were done, I am at last free. It was good, and I really liked working with the guys, but there is now a huge weight off my mind, and I can focus on doing some things well instead of watching stuff fall through the gaps from time to time.
This year's aim - to generate enough income that I can start repaying us the money that we used to start things going.