After the last update just a few weeks ago my HTC desire - which had been running very well - has started doing frequent re-starts of the HTC sense overlay. The phone itself appears fine, but the latest version of sense seems to keep failing and restarting.
It's still in warranty, so I don't really want to root it, but it is annoying. I'd also prefer not to do a full factory reset, as I don't know for certain that everything can be restored from SD card, nor that starting again will fix the issue. Just hoping there'll be another update along soon that will fix it.